Temporal distributions of rainfall, cases of leptospirosis requiring hospitalization, and Leptospira infections in Salvador, Brazil, February 2013–March 2015. A) Cumulative monthly rainfall. B) Monthly citywide cases of leptospirosis requiring hospitalization, which were reported to the national surveillance system and stratified according to confirmed (black bar), probable (gray bars), and unconfirmed (white bars) case status. Vertical lines represent the dates the 5 serosurveys were performed during the 2-year study. C) Cumulative incidence of citywide cases of leptospirosis requiring hospitalization during 4 biannual follow-up periods for a community-based cohort. D) Cumulative incidence of Leptospira infection among a cohort of 861 residents of an urban slum community within Salvador during 4 biannual follow-up periods. Error bars in panels C and D indicate 95% CIs.