Fig. 1. PV-CTC detection in early NSCLC.
a, TRACERx consort diagram. 149 patients consented for pulmonary vein blood sampling between June 2014 and March 2017. 27 samples were excluded because of failures in CellSearch® enrichment and enumeration. 22 patients were defined ineligible post-surgery and the remaining 100 patients constituted the final cohort for PV-CTC enumeration. b, Distribution of the number of PV-CTCs enumerated by CellSearch® from 100 patients with early NSCLC. LUAD (blue circle) and non-LUAD (red circle) patients are indicated. c, Heat map showing clinicopathological and PV-CTC detection data; Patients are stratified according to PV-CTC detection. Histological disease type is indicated by coloured bar above the heatmap.