Table 5. Some Example Large Open Datasets Relevant to Healthy and Atypical Development.
| Dataset | Disorder | No. of Subjects | Age, Years | Longitudinal Neuroimaging | Data Type | Availability |
|---|---|---|---|---|---|---|
| Child Mind Institute Healthy Brain Network (145) | Population | 10,000 | 5–21 | No | fMRI, sMRI, DWI, EEG | Ongoing, 664 subjects available in first release |
| IMAGEN (146) | Population | 2000 | 14–22 | Yes | fMRI, sMRI, DWI | Open to project proposals |
| NKI/Rockland Study (147) | Population | 1000 expected | 6–85 | Yes | rs-fMRI, sMRI, DWI | Ongoing, some data available |
| PNC (9) | Population | 1000 | 8–21 | Obtained but not openly available at present | fMRI, sMRI, DWI | Available |
| ADHD-200 (148) | ADHD | 491 HC, 285 ADHD | 7–21 | No | rs-fMRI, sMRI | Available |
| ABIDE I (149) | Autism | 539 ASD, 573 HC | 7–64 | No | rs-fMRI, sMRI | Available |
| ABIDE II (132) | Autism | 521 ASD, 593 HC | 5–64 | Partially (n = 38) | rs-fMRI, sMRI, DWI | Available |
| NUSDAST (150) | Schizophrenia | 171 SCZ, 170 HC, 44 SCZ siblings, 66 HC siblings | 13–67 | Yes | sMRI | Available |
Datasets were only included if they had large numbers of subjects (N > 300), with subjects from a range of ages, including significant numbers of subjects under 21 years of age, and are (or will be) openly available.
ABIDE, Autism Brain Imaging Data Exchange; ADHD, attention-deficit/hyperactivity disorder; ASD, autism spectrum disorder; DTI, diffusion tensor imaging; DWI, diffusion-weighted imaging; EEG, electroencephalography; fMRI, functional magnetic resonance imaging; HC, healthy control; NKI, Nathan S. Kline Institute for Psychiatric Research; NUSDAST, Northwestern University Schizophrenia Data and Software Tool; PNC, Philadelphia Neurodevelopmental Cohort; rs-fMRI, resting-state functional magnetic resonance imaging; SCZ, schizophrenia; sMRI, structural magnetic resonance imaging.