Fig. 5.

(A) Specimen showing Hürthle cell proliferative lesion lacking a fibrous capsule or adjacent nonlesional thyroid tissue. (B) The high-power view of Fig. 5A reveals trabecular growth of Hürthle cells without nuclear atypia, suggesting indeterminate follicular lesion with Hürthle cell changes (category IIId). Psammoma bodies (arrow) are found in a background of Hashimoto’s thyroiditis (C) and normal thyroid tissue (D). These specimens lack nuclear features of papillary carcinoma and can be interpreted as indeterminate lesion, not otherwise specified (category IIIe).