Table 3:
Relationship between Lithium vs. Other Mood Stabilizer exposure and outcome variables, adjusting for lasso-selected characteristics.
Outcome Variable | LI | OMS | OR/beta (Cl) | P |
---|---|---|---|---|
Suicidal Ideation and Attempts | ||||
Suicide Attempt n (%) | 17 (2%) | 63 (4%) | .51 (.28, .95) | .03 |
Suicidal Ideation n (%) | 56 (6%) | 171 (10%) | .69 (.45, 1.07) | .10 |
Mood Symptoms | ||||
Threshold Depression n (%) | 212 (24%) | 497 (28%) | .76 (0.55, 1.05) | .10 |
Mean PSR Depression Score (S.D.) | 2.0 (1.1) | 2.3 (1.2) | −.19 (−.32, −.06) | .004 |
Threshold Mania/Hypomania n (%) | 164 (19%) | 248 (14%) | 1.35 (0.95, 1.91) | .09 |
Mean PSR (Hypo)mania Score (S.D.) | 1.9 (1.8) | 1.9 (1.9) | .03 (−.04, .08) | .47 |
Psychosocial Functioning | ||||
Worst PSF (lower is better) | 10.2 (10.0) | 11.1 (11.2) | −55 (−.90, −.19) | .003 |
Other Outcomes | ||||
Hospitalization n (%) | 71 (8%) | 139 (8%) | 1.03 (.71, 1.51) | .87 |
Aggression score (BCS) | 4.7 (4.7) | 5.9 (4.7) | −1.1 (−1.7, −.5) | .0004 |
Substance Use Disorder n (%) | 45 (5%) | 105 (6%) | .65 (.33, 1.28) | .21 |
Note: BCS=Behavior Control Scale; LI=Lithium; OMS=Other Mood Stabilizer; PSR=Psychiatric Status Rating; PSF=Psychosocial Functioning.