Table 2.

OR with 95% CI for the development of EE by change in BMI

Characteristic	EE/all (%)	Crude OR (95% CI)*	Adjusted OR (95% CI)*,†
Change in BMI (kg/m2)
Loss	27/1,341 (2.0)	0.59 (0.38–0.90)	0.58 (0.38–0.90)
Stable	99/2,922 (3.4)	1.00 (Reference)	1.00 (Reference)
Mild gain	114/2,448 (4.7)	1.39 (1.06–1.83)	1.39 (1.06–1.84)
Moderate gain	36/412 (8.7)	2.73 (1.84–4.06)	2.80 (1.87–4.21)
P-value for trend‡		<0.001	<0.001

OR, odds ratio; CI, confidence interval; EE, erosive esophagitis; BMI, body mass index.

^*Using logistic regression analysis.

^†Adjusted for age, sex, baseline BMI, smoking status, alcohol consumption, physical activity, education, marital status, and Helicobacter pylori.

^‡Wald test for linear trend.