Table 3.

Odds ratio with 95% confidence interval^*,† for the development of erosive esophagitis by change in BMI in three groups stratified by baseline BMI

Characteristic	BMI <23.0 (n=2,735)	BMI 23.0–24.9 (n=2,196)	BMI ≥25.0 (n=2,192)
Change in BMI (kg/m2)
Loss	0.38 (0.15–0.97)	0.90 (0.46–1.78)	0.57 (0.27–1.19)
Stable	1.00 (Reference)	1.00 (Reference)	1.00 (Reference)
Mild gain	1.00 (0.62–1.63)	1.30 (0.78–2.15)	2.08 (1.29–3.36)
Moderate gain	1.69 (0.76–3.78)	3.30 (1.64–6.64)	3.92 (1.99–7.73)
P-value for trend‡	<0.001	<0.001	<0.001

Values are presented as odds ratio (95% confidence interval).

BMI, body mass index (kg/m²).

^*Using logistic regression analysis.

^†Adjusted for age, sex, baseline BMI, smoking status, alcohol consumption, physical activity, education, marital status, and Helicobacter pylori.

^‡P value for trend; Wald test for linear trend.