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. 2019 Dec 13;16(1):41–55. doi: 10.1007/s12015-019-09940-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Schematic representation of the bio-inspired dental regeneration strategy. The gene expression pattern during tooth development is obtained by biology and bioinformatics, and the development associated with spatial-temporal specific expression could be approached by using different control release strategies for regeneration purpose, and making the goal of tooth regeneration expectable