Figure 6.

Experimental design. Mice had access to running wheels during experimental weeks 2–25. Before the introduction of exercise intervention, during week 1, Open Field test (OF) and Clasping test (C) were conducted. Clasping tests were then repeated in weeks 3, 15, 19, 23 and 26. During week 20 Elevated Plus maze tests (EPM) were conducted. During weeks 21–22, Open Filed tests were performed. During weeks 25–26 Rotarod tests (R) were conducted. During the last week, week 26, a sucrose Preference test (SPT) was performed before the mice were sacrificed (+) to collect brain, blood and CSF samples.