Table 4.

Comparison of clinical factors between other and LAT1/IGFBP-5 high.

	Other	LAT1/IGFBP-5 High	P
Age (years)	67.95 ± 8.13	69.04 ± 7.88	0.5899
Grade 3 or greater (%)	64.29	96.15	0.0026*
pT stage 3 or greater (%)	53.66	100.00	< 0.0001*
CRP (mg/dL)	1.35 ± 2.38	188 ± 3.26	0.4584
LDH (U/L)	183.06 ± 50.23	219.91 ± 39.60	0.0064*
ALT (IU/L)	15.88 ± 27.45	9.41 ± 5.65	0.2796
AST (IU/L)	18.95 ± 14.21	17.50 ± 6.78	0.6523
ALP (IU/L)	134.93 ± 105.49	136.77 ± 47.43	0.9383
Hb (g/dL)	9.75 ± 1.72	10.10 ± 1.69	0.4259
Alb (U/L)	3.57 ± 1.28	3.31 ± 1.35	0.5007
NLR (ng/mL)	3.10 ± 1.49	4.43 ± 2.06	0.0070*
LAT1 staining score	0.66 ± 0.68	2.22 ± 0.40	< 0.0001*
IGFBP-5 staining score	0.98 ± 0.82	2.40 ± 0.50	< 0.0001*

Data are expressed as mean ± standard deviation unless otherwise indicated. Other = low intensity of the LAT1 and IGFBP-5 immunoreaction and only low intensity of the LAT1 or IGFBP-5 immunoreaction, LAT1/IGFBP-5 High = high intensity of the LAT1 and IGFBP-5 immunoreaction, pT stage = pathological tumour stage, CRP = C-reactive protein, LDH = lactate dehydrogenase, ALT = alanine transaminase, AST = aminotransferase, ALP = alkaline phosphatase, Hb = haemoglobin, Alb = albumin, NLR = neutrophil-to-lymphocyte ratio. *means significant difference.