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. 2020 Jan 28;10:1314. doi: 10.1038/s41598-020-58030-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of rat CDAA to human NASH mRNA datasets on pathway level. Analysis match of overrepresentation analyses of canonical pathways using IPA of all rat data and three selected human datasets. Data are filtered to give at least one hit in a human study and one rat CDAA time point with Benjamini-Hochberg adj. p value < 0.05. Left panel: Signaling pathways, right panel: metabolic pathways (see Supplementary Table S2 for details). Note: Due to different reference datasets, the p values of the analyses are not directly comparable.