Table 5.
Age-based classification between younger and older healthy adults in nine major brain networks for E2.
| FC Measure | D. DMN | V. DMN | L. ECN | R. ECN | A. Salience | P. Salience | Auditory | Language | Motor |
|---|---|---|---|---|---|---|---|---|---|
| Pearson’s Correlation | 45.28% | 56.60% | 52.83% | 66.03% | 75.47% | 62.26% | 58.49% | 58.49% | 56.60% |
| Cross-correlation | 54.72% | 52.83% | 54.72% | 60.37% | 79.24% | 58.49% | 58.49% | 54.72% | 54.71% |
| Coherence | 54.71% | 50.94% | 50.94% | 54.71% | 60.37% | 50.94% | 58.49% | 56.60% | 69.81% |
| Wavelet coherence | 49.06% | 52.83% | 52.83% | 54.71% | 67.92% | 50.94% | 62.26% | 54.71% | 52.83% |
| Mutual Information | 62.26% | 75.47% | 62.26% | 52.83% | 77.35% | 58.49% | 52.83% | 54.71% | 54.71% |
| Euclidean distance | 64.15% | 69.81% | 62.26% | 66.03% | 71.69% | 50.94% | 54.72% | 54.71% | 52.83% |
| Cityblock distance | 71.69% | 71.69% | 64.15% | 64.15% | 83.01% | 50.94% | 52.83% | 64.15% | 54.72% |
| DTW | 69.81% | 73.58% | 69.81% | 62.26% | 79.24% | 56.60% | 52.83% | 60.37% | 50.94% |
| EMD | 52.83% | 62.26% | 64.15% | 52.83% | 66.03% | 52.83% | 52.83% | 50.94% | 66.03% |
| Composite | 66.04% | 69.82% | 69.81% | 54.72% | 84.91% | 73.58% | 69.81% | 58.49% | 62.26% |
Note: Brain networks are defined by the Willard functional atlas with a support vector machine classifier. Performance represents accuracy levels (%) with a leave-one out testing. The highest performing FC measure is represented in bold for each network. Additional performance measures are included in Supplementary Table 2; D.DMN = dorsal default mode network; V.DMN = ventral default mode network; L.ECN = left executive control network; R.ECN = right executive control network; A.Salience = anterior salience; P.Salience = posterior salience; DTW = dynamic time warping; EMD = earth mover’s distance.