. 2020 Jan 22;10:3017. doi: 10.3389/fimmu.2019.03017

Table 2.

Salient technical tools available to discriminate steroid receptor-specific pathways.

	Progesterone receptor	Glucocorticoid receptor	Membrane progestin receptors (mPR)	Progesterone receptor membrane components (PGRMC)
Selective agonists	20α-dihydrodydrogesterone (DHD) (89)	Dexamethasone, betamethasone (15), ZK209614 (90)	progesterone conjugated to BSA (50)
Antagonist	non-selective: RU-486		–	–
	selective: ZK98299 (91), Ulipristal acetate (92), Org31710 (93)	selective: RU-43044 (94)
Mouse models for cell specific depletion	Pr^fl/fl (21)	Gr^fl/fl (9, 10)	–	Pgrmc1^fl/fl and Pgrmc2^fl/fl (30)