Table 3.
Changes of sTILs, PD-L1, MVD, and MPI in non-pCR group and pCR group after NAC.
| Parameter | Non-pCR group | pCR group | P | |
|---|---|---|---|---|
| sTILs change | 0.020 | |||
| Up | 34 (61.8) | 19 (95.0) | ||
| Down | 14 (25.5) | 1 (5.0) | ||
| Stable | 7 (12.7) | 0 (0.0) | ||
| CD8+T change | 0.037 | |||
| Up | 33 (60.0) | 18 (90.0) | ||
| Down | 14 (25.5) | 2 (10.0) | ||
| Stable | 8 (14.5) | 0 (0.0) | ||
| CD4+T change | 0.012 | |||
| Up | 35 (63.6) | 19 (95.0) | ||
| Down | 6 (10.9) | 1 (5.0) | ||
| Stable | 14 (25.5) | 0 (0.0) | ||
| FOXP3+Tregs change | 0.000 | |||
| Up | 25 (45.5) | 0 (0.0) | ||
| Down | 22 (40.0) | 17 (85.0) | ||
| Stable | 8 (14.5) | 3 (15.0) | ||
| PD-L1 change | 0.627 | |||
| Up | 13 (23.6) | 7 (35.0) | ||
| Down | 29 (52.7) | 9 (45.0) | ||
| Stable | 13 (23.6) | 4 (20.0) | ||
| MVD change | 0.478 | |||
| Up | 16 (29.1) | 3 (15.0) | ||
| Down | 37 (67.3) | 16 (80.0) | ||
| Stable | 2 (3.6) | 1 (5.0) | ||
| MPI change | 0.557 | |||
| Up | 36 (65.5) | 16 (80.0) | ||
| Down | 16 (29.1) | 4 (20.0) | ||
| Stable | 3 (5.5) | 0 (0.0) |