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. 2020 Jan 22;10:955. doi: 10.3389/fpsyt.2019.00955

Table 4.

Withdrawal severity after psychedelic-associated cannabis cessation or reduction in comparison with previous quit attempts. (n = 166).

Withdrawal Symptom n a Symptom Severity
Much less severe Less severe Same More severe Much more severe
n (%) n (%) n (%) n (%) n (%)
Lack of appetite 75 18 (24.0%) 13 (17.3%) 31 (41.3%) 12 (16.0%) 1 (1.3%)
Fatigue 87 24 (27.6%) 20 (23.0%) 30 (34.5%) 7 (8.0%) 6 (6.9%)
Headaches 70 19 (27.1%) 15 (21.4%) 25 (35.7%) 11 (15.7%) 0 (.0%)
Drowsiness 72 19 (26.4%) 16 (22.2%) 24 (33.3%) 11 (15.3%) 2 (2.8%)
Fever 24 4 (16.7%) 2 (8.3%) 17 (70.8%) 0 (.0%) 1 (4.2%)
Nausea 34 8 (23.5%) 6 (17.6%) 17 (50.0%) 3 (1.8%) 0 (.0%)
Tremors 41 11 (26.8%) 6 (14.6%) 16 (39.0%) 6 (14.6%) 2 (4.9%)
Increased heart rate 45 11 (24.4%) 10 (22.2%) 16 (35.6%) 4 (8.9%) 4 (8.9%)
Chills 35 9 (25.7%) 4 (11.4%) 16 (45.7%) 5 (14.3%) 1 (2.9%)
Seizures 18 3 (16.7%) 1 (5.6%) 14 (77.8%) 0 (.0%) 0 (.0%)
Hallucinations 30 4 (13.3.%) 3 (10.0%) 13 (43.3%) 7 (23.3%) 3 (10.0%)
Cravings 110 62 (56.4%) 20 (18.2%) 17 (15.5%) 6 (5.5%) 5 (4.5%)
Depression 113 45 (39.8%) 23 (20.4%) 20 (17.7%) 15 (13.3%) 10 (8.8%)
Confusion 70 23 (32.9%) 13 (18.6%) 17 (24.3%) 9 (12.9%) 8 (11.4%)
Heart pounding 49 17 (34.7%) 4 (8.2%) 16 (32.7%) 7 (14.3%) 5 (10.2%)
Difficulty concentrating 100 32 (32.0%) 25 (25.0%) 22 (22.0%) 10 (10.0%) 11 (11.0%)
Irritability 94 30 (31.9%) 27 (28.7%) 17 (18.1%) 15 (18.1%) 5 (5.3%)
Insomnia 110 32 (29.1%) 17 (15.5%) 26 (23.6%) 21 (19.1%) 14 (12.7%)
Restlessness 95 27 (28.4%) 22 (23.2%) 23 (24.2%) 17 (17.9%) 6 (6.3%)
Anxiety 100 28 (28.0%) 27 (27.0%) 20 (20.0%) 12 (12.0%) 13 (13.0%)
a

Sample size varies by symptom (range = 18–113), as some participants had never experienced particular withdrawal symptoms. Percentages were calculated based on the number of individuals who reported a particular withdrawal symptom.

Modal responses shown in bold type.