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. 2020 Jan 22;10:955. doi: 10.3389/fpsyt.2019.00955

Table 6.

Withdrawal severity after psychedelic-associated stimulant cessation or reduction in comparison with previous quit attempts. (n = 123).

Withdrawal Symptom n a Symptom Severity
Much less severe Less severe Same More severe Much more severe
n (%) n (%) n (%) n (%) n (%)
Fever 46 8 (17.4%) 9 (19.6%) 26 (56.5%) 1 (2.2%) 2 (4.3%)
Heart pounding 73 16 (21.9%) 21 (28.8%) 29 (39.7%) 4 (5.5%) 3 (4.1%)
Psychomotor retardation 75 20 (26.7%) 23 (30.7%) 27 (36.0%) 4 (5.3%) 1 (1.3%)
Increased appetite 87 15 (17.2%) 19 (21.8%) 31 (35.6%) 17 (19.5%) 5 (5.7%)
Drowsiness 87 17 (19.5%) 23 (26.4%) 30 (34.5%) 12 (13.8%) 5 (5.7%)
Unpleasant dreams 70 13 (18.6%) 22 (31.4.%) 23 (32.9%) 7 (10.0%) 5 (7.1%)
Increased heart rate 77 18 (23.4%) 24 (23.4%) 25 (32.5%) 8 (10.4%) 2 (2.6%)
Psychomotor agitation 69 19 (27.5%) 18 (26.1%) 21 (30.4%) 8 (11.6%) 3 (4.3%)
Difficulty concentrating 93 24 (25.8%) 25 (26.9%) 28 (30.1%) 10 (10.8%) 6 (6.5%)
Headaches 83 20 (24.1%) 22 (26.5%) 24 (28.9%) 11 (13.3%) 6 (7.2%)
Restlessness 89 19 (21.3%) 31 (34.8%) 20 (22.5%) 14 (15.7%) 5 (5.6%)
Confusion 68 16 (23.5%) 23 (33.8%) 22 (32.4%) 7 (10.3%) 0 (.0%)
Irritability 97 27 (27.8%) 31 (32.0%) 18 (18.6%) 15 (15.5%) 6 (6.2%)
Fatigue 88 20 (22.7%) 26 (29.5%) 26 (29.5%) 12 (13.6%) 4 (4.5%)
Insomnia 87 17 (19.5%) 24 (27.6%) 24 (27.6%) 13 (14.9%) 9 (10.3%)
Cravings 95 40 (42.1%) 22 (23.2%) 18 (18.9%) 8 (8.4%) 7 (7.4%)
Anxiety 95 33 (34.7%) 30 (31.6%) 16 (16.8%) 11 (11.6%) 5 (5.3%)
Depression 103 35 (34.0%) 29 (28.2%) 17 (16.5%) 13 (12.6%) 9 (8.7%)
a

Sample size varies by symptom (range = 46–103), as some participants had never experienced particular withdrawal symptoms. Percentages were calculated based on the number of individuals who reported a particular withdrawal symptom.

Modal responses shown in bold type.