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. 2020 Jan 22;13:78. doi: 10.3389/fninf.2019.00078

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Copyright © 2020 Mandino, Cerri, Garin, Straathof, van Tilborg, Chakravarty, Dhenain, Dijkhuizen, Gozzi, Hess, Keilholz, Lerch, Shih and Grandjean.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) A seed-based analysis of the anterior cingulate area in 98 resting-state fMRI scans reveals the topological distribution of the mouse default-mode network. The regions co-activating with the seed include the dorsal striatum, dorsal thalamus, retrosplenial, and posterior parietal areas. (B) The reproducibility of the default-mode network was assessed in 17 independent datasets consisting of 15 scans each. Overlapping one-sample t-test maps are summarized in a color-coded overlay. 12/17 datasets present converging topological features, the remaining five failed to present evidence of distal connectivity relative to the seed. Adapted with permission from Grandjean et al. (2019a).