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Animal preparation and anesthesia trends. (A) Animal fMRI relies mainly on anesthesia to help restrain animals. NHP remain the major species acclimated to awake fMRI. (B) Isoflurane is the principal anesthetic used for maintenance during fMRI recordings. However, the distribution of other agents change with species. (C) Medetomidine is growing to become the second most used agent behind isoflurane.
