Table 3. Sperm morphology (%) at follow-up times, after induced testicular and epididymal heating in volunteers and in controls.
Variables | Controls (n=27) | After heating | |||
---|---|---|---|---|---|
D165 (n=5) | D193 (n=5) | D215 (n=5) | D300 (n=5) | ||
Tapered head | 1 [0–3] | 3 [2–6] | 1 [0–2] | 1 [0–1] | 0 [0–1] |
Thin head | 5 [3–7] | 14 [10–18]* | 7 [7–16] | 6 [5–9] | 6 [5–10] |
Small round-head | 10 [7–15] | 14 [8–26] | 18 [18–21] | 15 [13–25] | 14 [9–21] |
Macrocephalic | 1 [0–2] | 3 [1–4] | 1 [0–1] | 0 [0–0] | 1 [1–1] |
Multiple heads | 1 [0–2] | 2 [2–3] | 2 [1–2] | 1 [0–3] | 2 [0–3] |
Abnormal post-acrosomal region | 25 [12–31] | 36 [34–39] | 22 [22–32] | 21 [20–21] | 21 [21–29] |
Abnormal acrosomal region | 36 [25–47] | 72 [54–80]* | 42 [41–54] | 41 [39–54] | 46 [40–56] |
Excess residual cytoplasm | 3 [2–6] | 8 [8–12] | 5 [4–5] | 5 [5–6] | 2 [2–5] |
Thin midpiece | 2 [0–3] | 2 [1–2] | 2 [1–2] | 1 [1–2] | 3 [1–4] |
Bent or misaligned midpiece | 17 [11–21] | 25 [21–27] | 23 [18–28] | 19 [16–24] | 16 [14–22] |
No tail | 1 [0–2] | 2 [2–3] | 1 [0–1] | 1 [1–1] | 1 [1–5] |
Short tail | 0 [0–1] | 1 [1–3] | 0 [0–1] | 0 [0–1] | 1 [1–1] |
Irregularly shaped tail | 0 [0–1] | 1 [0–4] | 0 [0–3] | 1 [1–2] | 0 [0–1] |
Coiled tail | 9 [4–13] | 13 [11–13] | 11 [9–17] | 10 [10–18] | 17 [9–22] |
Multiple tails | 1 [0–2] | 3 [3–4] | 2 [2–3] | 1 [1–1] | 2 [1–3] |
Normal spermatozoa (%) | 38 [26–44] | 11 [4–20]* | 26 [18–29] | 33 [21–37] | 33 [23–33] |
MAI | 1.86 [1.68–1.94] | 2.42 [2.1–2.73]* | 2.10 [1.84–2.16] | 2 [1.97–2.08] | 1.98 [1.91–2.04] |
Values are expressed as a median with an interquartile range [q1–q3]. *, values differ significantly from the control group values.