Fig. 3.

Adolescent male and female mice show impaired working memory in the T-maze delayed alternation test. (A and D) Male and female adolescent and adult mice require the same number of days to reach the criterion of completion during the training phase of the task; (B and E) however, when a working memory load is introduced in the form of a 15-s delay, both male and female adolescent mice need more days to reach the criterion of success than adult mice. (C and F) Overall, adult mice required less days to complete the task than adolescent mice. *p < 0.05; ^tp < 0.09. Male adolescent N = 8; Male adult N = 7; Female adolescent N = 8; Female adult N = 7.