Table 3. Prognostic capacities of changes induced by the first PP session.
| Parameters | AUROC (95% CI) | Best cutoff | Sensitivity (95% CI) (%) | Specificity (95% CI) (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|
| Absolute change | ||||||
| PaO2/FiO2 | 0.55 (0.43 to 0.67) | +68 mmHg | 59 (42 to 74) | 60 (45 to 74) | 56 | 63 |
| VD/VT | 0.51 (0.39 to 0.63) | –0.10 | 46 (31 to 63) | 65 (50 to 78) | 53 | 58 |
| ΔPRS | 0.63 (0.51 to 0.75) | –3 cmH2O | 76 (60 to 88) | 56 (41 to 71) | 60 | 73 |
| Relative change | ||||||
| PaO2/FiO2 | 0.55 (0.43 to 0.67) | +78% | 63 (47 to 78) | 54 (39 to 69) | 54 | 63 |
| VD/VT | 0.51 (0.39 to 0.63) | –46% | 88 (74 to 96) | 31 (19 to 46) | 52 | 75 |
| ΔPRS | 0.62 (0.50 to 0.73) | –14% | 76 (60 to 88) | 50 (35 to 65) | 56 | 71 |
AUROC, area under the receiver operator characteristics curve; PPV, positive predictive value; NPV, negative predictive value; CI, confidence interval; PaO2/FiO2, ratio between arterial oxygen tension and fraction of inspired oxygen; VD/VT, dead space fraction; ΔPRS, respiratory system driving pressure.