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. 2019 Dec;11(12):5274–5289. doi: 10.21037/jtd.2019.11.52

Table 5. Correlation analysis between CEUS characteristics and pathological grading.

Characteristics Pathological grading after NAC (n=22) Contingency
coefficient
P
1 2 3 4 5
Texture of enhancement 0.363 0.550
   Homogeneous 0 0 1 1 0
   Heterogeneous 1 6 7 2 4
Equal or low enhanced area inside 0.495 0.126
   Yes 1 2 1 0 0
   No 0 4 7 3 4
Boundary 0.497 0.115
   Clear 1 3 6 2 0
   Unclear 0 3 2 1 4
Shape 0.398 0.475
   Regular 0 2 3 2 0
   Irregular 1 4 5 1 4
Solar sign 0.564 0.020*
   Yes 0 1 4 0 4
   No 1 5 4 3 0
Invasion of skin 0.228 0.932
   Yes 0 1 3 1 1
   No 1 5 5 2 3
Invasion of muscle 0.322 0.777
   Yes 0 1 4 1 2
   No 1 5 4 2 2
Invasion of nipples 0.335 0.706
   Yes 0 1 3 1 0
   No 1 5 5 2 4
The largest cross section of the lesions in CEUS (cm)
   TD 3.93 3.94±0.96 4.5±1.86 4.59±2.52 3.75±1.61 −0.056 0.805
   APD 2.6 2.52±0.60 2.8±0.78 2.04±0.42 2.2±1.04 −0.208 0.353
Maximum area in CEUS (cm2) 9 6.15±2.32 8.89±4.36 6.21±4.15 6.65±5.02 −0.053 0.813
Maximum circumference in CEUS (cm) 11.3 10.76±1.83 13.03±5.66 12.41±6.29 11.66±5.89 0.042 0.854

CEUS, contrast-enhanced ultrasonography; NAC, neoadjuvant chemotherapy; TD, transverse diameter (cm); APD, anteroposterior diameter (cm).