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. 2019 Dec;11(12):5274–5289. doi: 10.21037/jtd.2019.11.52

Table 6. Correlation analysis between conventional ultrasonic characteristics and pathological grading.

Features Pathological grading after NAC (n=22) Contingency coefficient P
1 2 3 4 5
Type of lesions 0.277 0.829
   Mass type 1 5 6 2 4
   Non-mass type 0 1 2 1 0
Shape 0.336 0.636
   Regular 0 1 0 0 0
   Irregular 1 5 8 3 4
Echo texture 0.336 0.636
   Homogeneous 0 1 0 0 0
   Heterogeneous 1 5 8 3 4
Calcification 0.534 0.348
   Microcalcification 1 2 6 2 0
   Micro-and-macro calcification 0 1 0 0 1
   No-calcification 0 3 2 1 3
Cystic change 0.521 0.156
   Yes 1 0 1 0 1
   No 0 6 7 3 3
Peripheral hyperechoic halo 0.373 0.569
   Yes 0 5 6 2 2
   No 1 1 2 1 2
Aspect ratio 0.338 0.654
   >1 0 1 0 0 1
   ≤1 1 5 8 3 3
Posterior echo 0.492 0.628
   Enhancement 0 1 3 0 0
   Attenuation 0 2 2 0 2
   No change 1 3 3 3 2
Invasion of skin 0.335 0.706
   Yes 0 1 3 1 0
   No 1 5 5 2 4
Invasion of muscle 0.406 0.440
   Yes 0 1 4 1 0
   No 1 5 4 2 4
Invasion of nipples 0.228 0.932
   Yes 0 1 3 1 1
   No 1 5 5 2 3
Blood flow classification 0.338 0.654
   2 0 1 0 0 1
   3 1 5 8 3 3
RI 0.82 0.67±0.14 0.77±0.06 0.68±0.05 0.72±0.07 −0.206 0.359
The largest cross section (cm)
   TD 3.67 3.31±1.32 4.15±1.93 3.96±1.75 2.51±1.40 −0.149 0.520
   APD 2.30 2.20±0.82 2.44±0.89 1.62±0.43 1.66±0.67 −0.339 0.123
   ULD 3.58 2.95±0.95 3.25±1.81 3.52±0.95 1.89±1.06 −0.242 0.277
Maximum area (cm2) 7.72 4.13±1.91 6.14±3.18 5.19±3.60 3.21±2.70 −0.199 0.375
Maximum circumference (cm) 12.6 9.67±2.74 11.33±4.93 10.56±4.69 7.79±4.38 −0.163 0.468

NAC, neoadjuvant chemotherapy; RI, resistance index; TD, transverse diameter (cm); APD, anteroposterior diameter (cm); ULD, upper and lower diameter (cm).