Table 1. Clinicopathologic factors related to BRAF mutation in 1,199 patients with PTC.

Clinicopathologic factors	BRAF (+)	BRAF (−)	χ2/t-test	P	Spearman	P
Age (years)	791	408	0.608	0.436	0.099	0.001
Mean ± SD	43.8±12.0	46.7±13.0		<0.001
≤45	433	180
>45	358	228
Sex	791	408	268.1	<0.001	−0.052	0.074
Male	195	121
Female	596	287
Tumor size (cm)	888	427	22.2	<0.001	0.031	0.264
Mean ± SD	0.82±0.49	0.86±0.56		<0.001
<1.0	688	320
≥1.0	200	107
Multiplicity			134.7	<0.001	0.040	0.151
Absent	884	427
Present	4	0
Bilaterality			158.2	<0.001	0.108	0.001
Absent	791	408
Present	97	19

PTC, papillary thyroid carcinoma.