Table 2. The difference of contrast enhancement patterns between BRAF-positive and BRAF-negative nodules.

CEUS features	BRAF (+)	BRAF (−)	χ2	P	Spearman	P
Size of the enhanced lesions			22.2	<0.001	0.019	0.491
Larger	391	180
Similar	497	247
Degree of enhancement			1,556.7	<0.001	0.042	0.131
Significant enhancement	75	50
No significant enhancement	813	377
Method of enhancement			113.8	<0.001	0.077	0.005
Centripetal	336	128
Nonconcentric	552	299
Homogeneity of enhancement			51.0	<0.001	-0.024	0.392
Inhomogeneous	364	164
Homogeneous	524	263
Completeness of enhancement			1,115.2	<0.001	0.087	0.002
Incomplete	25	27
Complete	863	400
Wash out period			673.3	<0.001	-0.010	0.730
With wash out period	129	58
Non-wash out period	759	369
Boundary of the enhanced lesions			595.6	<0.001	0.032	0.248
Blurred	750	350
Well-defined	138	77
Shape of the enhanced lesions			1,049.9	<0.001	0.077	0.006
Irregular	851	394
Regular	37	33