Table 3. Primary and secondary endpoints of the randomized controlled clinical study.

Primary endpoint

Diagnostic yield

Secondary endpoint

Diagnostic yields for malignant and benign diseases

Time for finding lesions

Total operation time

Visibility rate with R-EBUS

Eligibility rate of tissue samples assessed by pathology

Factors affecting diagnostic yield

Sensitivity/specificity/positive predictive value/negative predictive value of lung cancer diagnosis

Incidence of complications related to the initial ENB procedure

R-EBUS, radial probe endobronchial ultrasound; ENB, electromagnetic navigation bronchoscopy.