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. Author manuscript; available in PMC: 2020 Jan 29.
Published in final edited form as: Cancer Res. 2016 Sep 26;77(2):579–589. doi: 10.1158/0008-5472.CAN-16-1281

Figure 1.

Figure 1.

Elevated SPINK6 protein level in the primary nasopharyngeal carcinoma correlated with shorter OS, DFS, and DMFS in the patients. A, The mRNA levels of SPINK6 in nasopharyngeal carcinoma (NPC) tissues were higher than the noncancerous nasopharyngeal tissues (NP), and even higher in lymph node metastases (LN). P value, result of unpaired t test. B, Expression of SPINK6 in nasopharyngeal carcinoma cells is shown. Top, mRNA level of SPINK6; bottom, protein level of SPINK6 in condition medium with relative gradation shown below the band. C, Different levels of SPINK6 protein detected by IHC are shown under both low and high magnification of a light microscope. Scale bars, 100 μm. D, Tissue microarray analyses of a cohort of 534 nasopharyngeal carcinoma patients diagnosed at M0 stage were conducted. The median follow-up time for this cohort of patients was 81 months.