Table 1.

Multivariate analysis of OS, DFS, and DMFS in nasopharyngeal carcinoma patients (Cox regression model)

	HR (95% CI)	P
OS
Age (>46 vs. ≤46)	1.548 (1.161–2.064)	0.003
Gender (female vs. male)	0.584 (0.406–0.840)	0.004
Clinical staging (III + IV vs. I + II)	3.543 (2.269–5.531)	<0.001
SPINK6 (high vs. low level)	1.379 (1.025–1.855)	0.034
DFS
T staging (T3–4 vs. T1–2)	1.964 (1.234–3.125)	0.004
SPINK6 (high vs. low level)	2.101 (1.378–3.206)	0.001
DMFS
Clinical staging (III + IV vs. I + II)	4.265 (1.699–10.706)	0.002
SPINK6 (high vs. low level)	2.555 (1.505–4.337)	0.001

Abbreviation: CI, confidence interval.