Table 3.
Correlation Analysis of Both Liver Stiffness by Transient Elastography and the Time From the Fontan Procedure With Laboratory and Hemodynamic Parameters
| Investigation (Reference) | Median (IQR) | Liver Stiffness | Time From Fontan | ||
|---|---|---|---|---|---|
| ρ | P Value | ρ | P Value | ||
| APRI (<0.7) | 0.5 (0.4–0.6) | 0.2565 | 0.04* | 0.000 | 1.0 |
| ALT (10–45) | 37.0 (30.0–43.0) | −0.1952 | 0.09 | −0.2178 | 0.06 |
| AST (15–40) | 36.0 (30.0–43.0) | −0.4492 | <0.01* | −0.5489 | <0.01 |
| GGT (12–33) | 47.0 (32.0–64.0) | 0.0416 | 0.7 | 0.0895 | 0.4 |
| Bilirubin (2–17) | 11.0 (8.5–13.0) | 0.0762 | 0.8 | −0.0843 | 0.8 |
| Alkaline phosphatase (130–525) | 186.0 (140.0–240.0) | −0.1376 | 0.2 | −0.3881 | <0.01 |
| Platelets (180–440) | 211.0 (154.0–248.0) | −0.3853 | <0.01* | −0.1889 | 0.1 |
| Albumin (37–56) | 45.0 (41.0–47.0) | 0.0609 | 0.6 | −0.0271 | 0.8 |
| Fontan pressure, mm Hg | 13.0 (12.0–14.0) | 0.3241 | 0.3 | 0.5825 | 0.04 |
| PVR, mm Hg·min/L | 1.4 (0.9–1.8) | −0.5819 | 0.2 | −0.1009 | 0.8 |
ALT indicates alanine aminotransferase; APRI, aspartate transaminase to platelet ratio index; AST, aspartate aminotransferase; GGT, gamma‐glutamyl transferase; IQR, interquartile range; PVR, pulmonary vascular resistance.