Table 4.
Event | Any grade | Grade 3 | Grade ≥ 4 |
---|---|---|---|
Any toxicity n (%) | |||
Nausea Nausea | 11 (34.4) | 0 (0) | 0 (0) |
Fatigue | 16 (50) | 1 (3.1) | 0 (0) |
Neutropenia | 15 (47) | 2 (6.3) | 10 (31.3) |
Mucositis | 6 (18.7) | 1 (3.1) | 0 (0) |
Alopecia Alopecia | 32 (100) | 0 (0) | 0 (0) |
Vomiting | 5 (15.6) | 0 (0) | 0 (0) |
Anaemia Anaemia | 29 (90.6) | 7 (21.9) | 0 (0) |
Leukopenia Leukopenia | 21 (65.6) | 10 (31.3) | 2 (6.3) |
Constipation | 7 (21.9) | 0 (0) | 0 (0) |
Diarrhea Diarrhea | 2 (6.3) | 0 (0) | 0 (0) |
Decreased appetite Decreased appetite | 10 (31.3) | 0 (0) | 0 (0) |
Abdominal pain | 3 (3.4) | 1 (3.1) | 1 (3.1) |
Pyrexia | 3 (9.4) | 0 (0) | 2 (6.3) |
Musculoskeletal pain | 2 (6.3) | 0 (0) | 0 (0) |
Febrile neutropenia | 4 (12.5) | 1 (3.1) | 2 (6.3) |
Infections and infestations | 7 (21.9) | 1 (3.1) | 3 (9.4) |
Infusion-related reaction | 1 (3.1) | 0 (0) | 0 (0) |
Olaratumab-related toxicitiy | 0 (0) | 0 (0) | 0 (0) |
Toxicity leading to discontinuation | 1 (3.1) | 0 (0) | 1 (3.1) |
Cardiac dysfunction | 0 (0) | 0 (0) | 0 (0) |
Toxicity was assessed according to the National Cancer Institute (NCI) criteria v5.0