Table 2.
Hazard ratios (95% CI) for all-cause mortality according to baseline MMSE Score
| MMSE Score | Death | Hazard Ratio(95% CI) | ||||
|---|---|---|---|---|---|---|
| Model1 | Model2 | Model3 | Model4 | Model5 | ||
| 2002–2008 | ||||||
| Cognitive impairment by Education | 5069 (49.9) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) |
| MMSE by Education | 3216 (85.7) | 2.88 (2.75,3.01) | 1.49 (1.41,1.56) | 1.44 (1.37,1.51) | 1.33 (1.26,1.40) | 1.32 (1.25,1.39) |
| MMSE 24 to 30 | 3630 (45.3) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) |
| MMSE<24 | 4655 (81.8) | 2.85 (2.72,2.97) | 1.54 (1.47,1.62) | 1.48 (1.41,1.56) | 1.39 (1.32,1.46) | 1.38 (1.31,1.45) |
| MMSE 24 to 30 | 3630 (45.3) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) |
| MMSE 18 to 23 | 1685 (71.6) | 2.12 (2.00,2.25) | 1.38 (1.30,1.47) | 1.34 (1.26,1.42) | 1.29 (1.21,1.37) | 1.28 (1.20,1.37) |
| MMSE<18 | 2970 (87.4) | 3.56 (3.39,3.74) | 1.69 (1.60,1.79) | 1.62 (1.53,1.72) | 1.48 (1.40,1.58) | 1.48 (1.39,1.57) |
| 2008–2014 | ||||||
| Cognitive impairment by Education | 4454 (47.1) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) |
| MMSE by Education | 3711 (84.2) | 2.80 (2.68,2.92) | 1.53 (1.45,1.60) | 1.37 (1.30,1.44) | 1.29 (1.22,1.36) | 1.26 (1.19,1.32) |
| MMSE 24 to 30 | 3630 (45.3) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) |
| MMSE<24 | 4805 (79.2) | 2.73 (2.61,2.86) | 1.52 (1.44,1.59) | 1.37 (1.30,1.44) | 1.30 (1.23,1.37) | 1.27 (1.20,1.34) |
| MMSE 24 to 30 | 4409 (43.4) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) | 1(Reference) |
| MMSE 18 to 23 | 1282 (66.2) | 1.92 (1.80,2.05) | 1.30 (1.22,1.39) | 1.25 (1.17,1.34) | 1.22 (1.14,1.30) | 1.20 (1.12,1.28) |
| MMSE<18 | 3523 (85.1) | 3.25 (3.10,3.41) | 1.65 (1.56,1.74) | 1.46 (1.38,1.55) | 1.36 (1.28,1.45) | 1.32 (1.25,1.41) |
Note: The values of cognitive impairment are n and mortality rate in brackets(%); CI confidence interval, MMSE Mini-Mental State Examination, ADL activities of daily living. Cognitive impairment by Education: < 18 was used to define cognitive impairment for participants who didn’t receive any formal education, < 21 for participants who received 6 years of education or less, and < 25 for participants who received more than 6 years of education
*Hazard ratio (95% CI) was calculated from Cox models
Model1: Unadjusted
Model2: Age + sex
Model3: Model2 + Marry+Living alone+Educational level + Exercise+Smoke+Drink
Model4: Model3 + ADL + Depression
Model5: Model4 + Medical service + Economic status