Table 3.
The subgroup analyses of hazard ratios (95% CI) for all-cause mortality according to baseline MMSE score
| MMSE | 2002–2008 | P-interaction | 2008–2014 | P-interaction | |
|---|---|---|---|---|---|
| Cohort | / | P = 0.254 | |||
| MMSE 18 to 23 | 1.28 (1.20,1.37) | 1.20 (1.12,1.28) | |||
| MMSE<18 | 1.48 (1.39,1.57) | 1.32 (1.25,1.41) | |||
| Sex | P = 0.663 | P = 0.810 | |||
| Male | MMSE 18 to 23 | 1.26 (1.14,1.39) | 1.20 (1.08,1.34) | ||
| MMSE<18 | 1.42 (1.29,1.57) | 1.23 (1.11,1.36) | |||
| Female | MMSE 18 to 23 | 1.31 (1.21,1.42) | 1.21 (1.10,1.32) | ||
| MMSE<18 | 1.51 (1.40,1.63) | 1.40 (1.29,1.51) | |||
| Age | P < .001 | P < .001 | |||
| 65–79 | MMSE 18 to 23 | 1.41 (1.16,1.72) | 1.63 (1.29,2.06) | ||
| MMSE<18 | 2.15 (1.64,2.83) | 1.79 (1.33,2.41) | |||
| 80–89 | MMSE 18 to 23 | 1.27 (1.14,1.42) | 1.17 (1.04,1.33) | ||
| MMSE<18 | 1.75 (1.56,1.97) | 1.33 (1.17,1.52) | |||
| 90–99 | MMSE 18 to 23 | 1.26 (1.14,1.40) | 1.16 (1.05,1.29) | ||
| MMSE<18 | 1.44 (1.31,1.59) | 1.39 (1.27,1.53) | |||
| 100+ | MMSE 18 to 23 | 1.09 (0.97,1.24) | 0.94 (0.81,1.09) | ||
| MMSE<18 | 1.29 (1.16,1.43) | 1.11 (0.99,1.24) |
Note: CI confidence interval, MMSE Mini-Mental State Examination
Reference: MMSE 24 to 30
*Hazard ratio (95% CI) was calculated from cox models after adjust age, sex, marry, living alone, educational level, exercise, smoke, drink, ADL, depression, medical service and economic status