Table 1.
Cohorts included in Asthma BRIDGE. Continuous variables are reported as means with (+/− standard deviation). Binary variables are reported as counts with (percentage of cohort)
| GRAAD | CAG | CARE | p-value | |
|---|---|---|---|---|
| N | 35 | 25 | 58 | |
| CACS | 13.97 (+/− 8.01) | 12.83 (+/− 6.38) | 8.12 (+/− 5.16) | 5.70E-05 |
| Age | 42.94 (+/− 12.70) | 38.52 (+/− 13.35) | 13.49 (+/− 3.45) | 1.30E-29 |
| Sex (# Male) | 9 (25.71%) | 6 (24.00%) | 40 (68.97%) | 1.10E-05 |
| Race | ||||
| Non-Hispanic White | 0 (0.00%) | 4 (16.00%) | 35 (60.34%) | 2.00E-09 |
| African American | 30 (85.71%) | 20 (80.00%) | 8 (13.79%) | 3.70E-13 |
| Hispanic | 0 (0.00%) | 0 (0.00%) | 9 (15.52%) | 0.0065 |
| Other/Mixed | 5 (14.29%) | 1 (4.00%) | 6 (10.34%) | 0.43 |
| Age Asthma Onset | 18.25 (+/− 16.22) | 5.73 (+/− 7.79) | 2.16 (+/− 2.09) | 1.50E-11 |
| Atopy | 12 (34.29%) | 9 (36.00%) | 34 (58.62%) | 0.036 |
| Intra-Uterine Smoke | 5 (14.29%) | 5 (20.00%) | 3 (5.17%) | 0.11 |
| Environmental Smoke Exposure | 21 (60.00%) | 12 (48.00%) | 9 (15.52%) | 2.80E-05 |
| Ever Smoker | 13 (37.14%) | 3 (12.00%) | 0 (0.00%) | 2.60E-06 |
P-values for continuous outcomes are from ANOVA, binary outcomes are from chi-squared tests. CACS: Chronic Asthma Control Score. CARE: Childhood Asthma Research and Education study. CAG: Chicago Asthma Genetics study. GRAAD: Genomic Research on Asthma in the African Diaspora