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. 2020 Jan 28;18:11. doi: 10.1186/s12915-019-0731-8

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9. — Phylogenetic tree of teleost Toll-like receptor protein sequences. A maximum likelihood phylogenetic tree run with the JTT substitution model and 500 bootstrap replicates on the transmembrane, linker, and TIR domain of all TLRs found in a selected set of teleosts in the Ensembl database, the Atlantic cod genome version 2, and all manually investigated Gobiiformes. A TLR sequence from the lancelet Branchiostoma belcheri was used as an outgroup and the root was placed upon its corresponding branch. Green triangles, Atlantic cod. Orange circles, round goby. Gray box, TLR22 and TLR23