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. 2020 Jan 28;20:64. doi: 10.1186/s12885-020-6537-9

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© The Author(s). 2020

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Fluorescence imaging with EP-HMRG of the tumor opening on the squamous epithelium. a Endoscopic imaging with white light before endoscopic submucosal dissection (ESD). b Magnifying narrow band imaging (M-NBI). c Endoscopic imaging with white light after ESD. The squamocolumnar junction (SCJ) is shown as a yellow line. d Fluorescence imaging after EP-HMRG spraying. e Pathological feature of the lesion extending under the squamous epithelium (hematoxylin and eosin staining). Arrows indicate the tumor opening on the squamous epithelium. Scale bars of (c and d), 5 mm. Scale bars of (e), 200 μm. The arrowheads of each color in (a–d) correspond to those of the same color in each case. The dotted circles indicate columnar epithelium without atypia (case #12)