Figure 1.

Visual overview of posttransplant IR in terms of time and graft source. Comprehensive IR data are summarized in supplemental Table 2. (A-B) ALC and CD20⁺ B- cell, CD4⁺CD45RA⁺ T-cell, and NK-cell counts (expressed as CD3⁻CD56⁺ and CD16⁺CD57⁻) were significantly higher during the early phase in all UCB recipients (all P < .001). In contrast to NK cells, the observation of CD8⁺ T-cell recovery was delayed in UCB recipients compared with that in BM and PBSC recipients. However, CD4⁺ T-cell expansion was temporally confirmed in memory T-cell and effector T-cell subsets in UCB recipients, and the overall difference in graft source–related IR gradually decreased over time.