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Expansion of key cell subsets; namely, CD20+B cells, CD8+CD11b−T cells, and CD16+CD57−NK cells, significantly positively affected 2-year OS. There were no significant differences in CIR or proportions of high vs low cell counts for CD20+ B cell and CD8+CD11b- T cell subsets. NRM benefits were found to be lower (range, 17%-21%) in patients with early IR of these cells. CIR was confirmed to be approximately 26% lower in patients with early IR of CD16+CD57− NK cells.
