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(A) mRNA levels of Mfn-2 and SP1 in SMMC-7721 cells transfected with Mfn-2. (B) SP1 binding with PITPNM3 promoter was significantly reduced in SMMC-7721 cells after transfection with Mfn-2 as determined by ChIP analysis. Mfn-2 – mitofusin-2; SP1 – simian virus 40 promoter factor 1; PITPNM3 – phosphatidylinositol transfer protein 3; ChIP – chromatin immunoprecipitation.
