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. 2020 Jan 22;10:3120. doi: 10.3389/fmicb.2019.03120

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Copyright © 2020 Martín and Liras.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Signal integration sites upstream of S. coelicolor amtB gene. Interaction of the regulatory proteins GlnR (green sphere), PhoP (blue sphere), MtrA (purple sphere), and AfsQ1 (orange sphere) on the amtB promoter region. The binding sites of GlnR, PhoP, MtrA, and AfsQ1 on the a1-b1, a2-b2, and a3-b3 sites are indicated with green, blue, purple, and orange horizontal bars, respectively. The transcription start point (P1) and the translation start point (tsp) of amtB are indicated. Positive regulation is indicated by arrows and negative regulations by black spheres. The consensus GlnR binding sequences are boxed. See text for additional details.