Table 2.
Effect of natural cell deficient on ginseng berry polysaccharide portion-induced inhibition of lung cancer.
| Group | Number of lung tumor | ||
|---|---|---|---|
| GBPP (100 μg/mouse) | |||
| Colony (mean ± SD) |
Range (n = 5) | Growth % | |
| Tumor control (untreated) | 58.2 ± 6.9 | 50, 52, 61, 62, 66 | 100.0 ± 11.8c |
| GBPP only | 30.4 ± 4.0 | 25, 28, 31, 33, 35 | 50.8 ± 9.4d |
| Anti-asialo GM1 control | 131.0 ± 9.2 | 118, 126, 134, 135, 142 | 225.1 ± 15.8a |
| Anti-asialo GM1 with GBPP | 82.6 ± 6.0 | 75, 79, 82, 87, 90 | 141.9 ± 10.4b |
To deplete NK cells in vivo, rabbit anti-asialo GM1 serum was injected into mice 1 and 3 days before inoculation of B16BL6 melanoma cells. Mice were treated with GBPP (100 μg, i.v.) 2 days before tumor inoculation. Mice were sacrificed 14 days after tumor inoculation for evaluation. a∼dSuperscripts express significant differences between groups (P < 0.05), as determined by Duncan’s multiple range test.