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. 2019 Nov 26;7:365. doi: 10.3389/fbioe.2019.00365

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Copyright © 2019 Gu, Ci, Zhang, Su, Lv, Chen, Liu, Zhang, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Feature display of target genes and circRNAs that interact with differentially expressed miRNAs. (A) The target genes expression of differential expression miRNAs between breast cancer samples and normal samples. Gene expression values were log2 transformed after adding a pseudo-value of 1 to avoid infinite values. Red indicates breast cancer samples, blue indicates normal samples. (B) DNA methylation cluster analysis of target genes bound by differentially expressed miRNAs. Red represents breast cancer samples, blue represents normal samples. (C) DNA methylation cluster analysis of circRNA host genes that interact with differentially expressed miRNAs. Red indicates breast cancer samples, and blue indicates normal samples.