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. 2018 Aug 27;33(1):1360–1373. doi: 10.1096/fj.201800615RR

Figure 1.

Figure 1

The behavioral differences between WT and MrgprD−/− mice. A) Von Frey testing during 14 d on WT and MrgprD−/− mice after CCI or sham injury (control). Values represent the changes from the baseline MWTs that were recorded on d 0 after CCI. B) The MWTs on d 7 after CCI. C) Radiant heat stimulus testing over 14 d after CCI or sham injury. Values represent the change from the baseline TWL values that were recorded on d 0 after the procedure. D) The TWL values on the d 7 were compared. E) The cold responses in the ipsilateral paws of MrgprD−/− mice were significantly lower than that of WT mice during 14 d after CCI. F) The aversive response score of WT mice and MrgprD−/− mice in CCI models on d 7 (n = 7). *P < 0.05, **P < 0.01, ***P < 0.001, WT vs. MrgprD−/−, by 2-way repeated-measures ANOVA, factorial design.