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. 2018 Aug 27;33(1):1360–1373. doi: 10.1096/fj.201800615RR

Figure 2.

Figure 2

The expression of MrgprD increased in a CCI-induced neuropathic pain model. EGFP+ neurons at the level of L4 DRGs were imaged in the naive (A), sham (B), and CCI (C) groups at d 14. Scale bar, 20 µm. D) The percentage of MrgprD+ neurons in L4 DRGs. E) The results of real-time PCR show the up-regulated transcriptional expression of MrgprD in the CCI mice in comparison with the naive and sham-injured counterparts. F) The percentage of β-alanine–responsive neurons in L4 DRGs from the 3 groups (% of cultured neurons; n = 3 per group). *P < 0.05, ***P < 0.001, by 1-way repeated-measures ANOVA.