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Increased binding of NF-κB to iNOS and Cox2 promoter in Crth2−/− RAW264.7 cells. ChIP of NF-κB p65 on iNOS (A) and Cox2 (B) promoters is compared with immunoprecipitation of IgG (negative control) in cells treated with LPS (100 ng/ml) for 8 h. Data represent mean fold enrichments. Data are means ± sem of technical triplicate. *P < 0.05 (Student’s t test).
