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. 2020 Jan 29;15(1):e0228042. doi: 10.1371/journal.pone.0228042

Table 3. Practitioners’ comfort in implementing the renewed program in the pre- and post-renewal samples*.

Key components Questions/indicators Pre-renewal Post-renewal Crude RR (95% CI) P-value Adjusted RR (95% CI) P-value
n % n %
Age and interval 1. Only offering routine cervical screening to women 25 years and over 108/156 69.2 151/175 86.3 1.25 (1.11 to 1.41) <0.001 1.20 (1.06 to 1.36) 0.005α
2. Screening HPV negative women every 5 years 131/157 83.4 159/175 91.0 1.09 (1.00 to 1.19) 0.04 1.05 (0.96 to 1.15) 0.26β
Sample collection 3. Collecting only a liquid based sample (not preparing a slide) 139/157 88.5 158/174 91.0 1.03 (0.95 to 1.10) 0.50 1.02 (0.95 to 1.10) 0.57£
Referral pathways 4. Referring all HPV16/18 positive women for colposcopy regardless of their cytology result 117/153 76.5 148/175 84.6 1.11 (0.99 to 1.23) 0.06 1.09 (0.99 to 1.21) 0.08£
5. Not referring women with oncogenic HPV non 16/18positive tests who have low grade/negative cytology for colposcopy 63/152 41.4 108/173 62.4 1.51 (1.21 to 1.88) <0.001 1.35 (1.10 to 1.69) 0.01Ψ
Self-collection 6. Recommending self-collection to an under-screened woman who refuses a practitioner-collected cervical sample 73/156 46.8 101/176 57.4 1.23 (0.99 to 1.51) 0.05 1.09 (0.87 to 1.37) 0.44
7. Having to wait to offer a repeat self-collection until the woman is overdue again (7 years since last screen) 29/152 19.1 53/175 30.2 1.59 (1.07 to 2.36) 0.023 1.30 (0.86 to 1.97) 0.21α

* Non responders removed from each item denominator

α Adjusted for place of practice

β Adjusted for place of practice, role and years in practice

£ Adjusted for role and years in practice

Ψ Adjusted for place of practice and role in practice

€ Adjusted for place of practice and an interaction between the renewal time period and place of practice (p = 0.045).