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. 2020 Jan 29;15(1):e0228102. doi: 10.1371/journal.pone.0228102

Table 2. Association between TB infection and individual, household, and community-level predictors in children and adolescents in 9 rural communities in rural Uganda.

  OR(95% CI) aOR (95%CI)
Individual-level factors
Age
    5–9 ref ref
    10–14 1.2 (0.9–1.8) 1.2 (0.9–1.8)
    15–19 2.9 (2.0–4.1)**** 3.1 (2.2–4.5)****
Gender
    Male ref ref
    Female 1.1 (0.8–1.4) 1.1 (0.8–1.4)
Lowest wealth tertile
    Yes 1.9 (1.3–2.8)*** 2.0 (1.3–2.9)***
HIV status
    negative ref ref
    positive 0.3 (0.1–1.2)* 0.2 (0.05–0.9)**
    unknown/not tested 1.1 (0.5–1.8) 1.2 (0.7–2.0)
BCG vaccination 1.5 (0.7–3.0)
Mother with HIV (possible HIV-exposed uninfected child) 1.0 (0.6–1.6)
Household-Level Factors
Proxies of Household TB Transmission
Household TB contact 3.4 (1.3–8.9)** 3.2 (1.3–7.6)****
Mother's TST status
    negative ref ref
    positive 2.3 (1.3–4.0)*** 2.2 (1.2–3.9)***
    unknown/mother not tested 1.6 (0.9–2.3)* 1.5 (0.9–2.6)
Another child (age<15 years) in household with positive TST Ω
    0 children ref ref
    1 or more child 7.4 (5.2–10.6)**** 6.5 (4.6–9.2)****
Characteristics of Household Members
Household member with HIV 0.9 (0.7–1.3)
≥1 household member lives outside of community for 6 months or more 1.2 (0.8–1.8)
> = 1 household members drink alcohol 1.4 (1.0–1.9)** 1.4 (1.0–1.9)*
School and Community-Level Factors
Boarding School or attends school outside community 2.4 (1.4–3.6)**** 1.7 (1.0–2.9)**
Occupation outside of home (age ≥15 years) 1.6 (1.0–2.5)** 1.2 (0.7–2.1)

OR = Odds Ratio; aOR = adjusted Odds Ratio; CI = Confidence Interval; ref = reference group; BCG = Bacilli Calmette Guérin; TST = tuberculin skin test

adjusted by age, gender, wealth, HIV status, and household TB contact

▵Only available for children 5–11

* p-value: ≤0.1

**p-value: ≤0.05

***p-value: <0.01

****p-value: <0.001