Table 2. Association between TB infection and individual, household, and community-level predictors in children and adolescents in 9 rural communities in rural Uganda.
OR(95% CI) | aOR (95%CI)† | |
---|---|---|
Individual-level factors | ||
Age | ||
5–9 | ref | ref |
10–14 | 1.2 (0.9–1.8) | 1.2 (0.9–1.8) |
15–19 | 2.9 (2.0–4.1)**** | 3.1 (2.2–4.5)**** |
Gender | ||
Male | ref | ref |
Female | 1.1 (0.8–1.4) | 1.1 (0.8–1.4) |
Lowest wealth tertile | ||
Yes | 1.9 (1.3–2.8)*** | 2.0 (1.3–2.9)*** |
HIV status | ||
negative | ref | ref |
positive | 0.3 (0.1–1.2)* | 0.2 (0.05–0.9)** |
unknown/not tested | 1.1 (0.5–1.8) | 1.2 (0.7–2.0) |
BCG vaccination | 1.5 (0.7–3.0) | |
Mother with HIV (possible HIV-exposed uninfected child)▵ | 1.0 (0.6–1.6) | |
Household-Level Factors | ||
Proxies of Household TB Transmission | ||
Household TB contact | 3.4 (1.3–8.9)** | 3.2 (1.3–7.6)**** |
Mother's TST status ▵ | ||
negative | ref | ref |
positive | 2.3 (1.3–4.0)*** | 2.2 (1.2–3.9)*** |
unknown/mother not tested | 1.6 (0.9–2.3)* | 1.5 (0.9–2.6) |
Another child (age<15 years) in household with positive TST Ω | ||
0 children | ref | ref |
1 or more child | 7.4 (5.2–10.6)**** | 6.5 (4.6–9.2)**** |
Characteristics of Household Members | ||
Household member with HIV | 0.9 (0.7–1.3) | |
≥1 household member lives outside of community for 6 months or more | 1.2 (0.8–1.8) | |
> = 1 household members drink alcohol | 1.4 (1.0–1.9)** | 1.4 (1.0–1.9)* |
School and Community-Level Factors | ||
Boarding School or attends school outside community | 2.4 (1.4–3.6)**** | 1.7 (1.0–2.9)** |
Occupation outside of home (age ≥15 years) | 1.6 (1.0–2.5)** | 1.2 (0.7–2.1) |
OR = Odds Ratio; aOR = adjusted Odds Ratio; CI = Confidence Interval; ref = reference group; BCG = Bacilli Calmette Guérin; TST = tuberculin skin test
†adjusted by age, gender, wealth, HIV status, and household TB contact
▵Only available for children 5–11
* p-value: ≤0.1
**p-value: ≤0.05
***p-value: <0.01
****p-value: <0.001