. Author manuscript; available in PMC: 2021 Jan 1.

Published in final edited form as: Arch Dermatol Res. 2019 Oct 28;312(1):1–4. doi: 10.1007/s00403-019-02001-z

Table I.

Microneedling effects on Collagen I and IGF-1 mRNA levels and numbers of dual-positive Ki67+/TD+ basal keratinocytes following UVB in geriatric skin.

	Fold Increase in mRNA (Treated/Control)		Ki67+/TD+ cells per 100 Basement Membrane		% Decrease in Ki67+/TD+ cells on wounded skin
Subject (M/F)	COLIA	IGF-1	Control	Treated	% Decrease in Ki67+/TD+ cells on wounded skin
1 (M)	1.33	1.65	0.37	0.11	70.2
2 (M)	7.47	4.71	0.17	0.01	94.1
3 (F)	2.53	0.99	0.20	0.00	100
4 (M)	6.20	5.12	0.29	0.00	100
5 (M)	2.26	1.42	0.64	0.04	93.8
6 (F)	3.98	0.94	0.16	0.10	37.5
7 (M)	10.85	5.32	0.16	0.00	100
8 (F)	1.08	0.81	UNDET	UNDET	UNDET
9 (M)	1.70	1.93	UNDET	UNDET	UNDET
AVG	4.16	2.54	0.28	0.04	85.1
SEM	1.12	0.64	0.07	0.02	8.9

M/F; male/female; UNDET; data not available due to technical reasons.