TABLE 4.
Clinical performance of the three commercial kits in detecting macrolide resistance among 154 specimens with M. genitalium positivity as detected by the three commercial kits and 23S rRNA sequencing data
| Commercial kit | 23S rRNA mutation | 23S rRNA sequencing |
% sensitivity (95% CI) | % specificity (95% CI) | |
|---|---|---|---|---|---|
| No. mutated | No. WTa | ||||
| S-DiaMGRes Diagenode | Present | 80 | 2 | 100 (95.4–100) | 97.3 (90.7–99.3) |
| Absent | 0 | 72 | |||
| RealAccurate TVMGres Pathofinder | Present | 76 | 2 | 95.0 (87.8–98.0) | 97.3 (90.7–99.3) |
| Absent | 4 | 72 | |||
| ResistancePlus MG SpeeDx | Present | 80 | 4 | 100 (95.4–100) | 94.6 (86.9–97.9) |
| Absent | 0 | 70 | |||
WT, wild type.