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. 2020 Jan 29;6(5):eaax2285. doi: 10.1126/sciadv.aax2285

Fig. 5. Cytokine production following stimulation with 5 and 1 with or without costimulation of LPS.

Fig. 5

Cytokine production is expressed as pg/mL ± SD. (A) Production of IL-1β stimulated by LPS (0.1 μg/ml), silica (125 μg/ml), peptide 1 (0.1 mg/ml), and compound 5 (0.1 mg/ml). (B) Production of TNF stimulated by LPS (0.001 μg/ml), peptide 1 (0.1 mg/ml), and compound 5 (0.1 mg/ml). Positive control: cells stimulated with LPS alone or in combination with silica. Negative control: untreated cells. Cells were prestimulated with LPS for 3 hours followed by either 6 hours of stimulation with silica or 4 hours of stimulation with 5 and control peptide 1. ND, not detectable.